Ngày 11 / 2 / 2016

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NEW LAB, FAST SERVICE, LOW FEE

    NEW LAB

 One of the main features of high technologies nowadays is the fast speed of development. DNA technology is not an exception. In order to catch up with international standards, the laboratory of the Center for Genetic Analysis and Technology (CGAT) has been upgraded several times over 11 years of operation. The third upgrade was just conducted in September 2015 to meet the rising needs of the society in DNA paternity and relationship identification, remains DNA testing and diagnosis of genetic diseases… The upgraded laboratory strictly meets the two most important standards of a laboratory of molecular biology, including: (1). Advanced equipment. The equipment and technologies for genetic analysis are imported from well-known manufacturers of the United Stage, United Kingdom, Germany and Japan… (2) The workflow of a DNA lab must strictly follow the international standards. All activities including sample collection, DNA extraction, DNA amplification and data analysis are performed in separated and specialized rooms in order to ensure the unidirectional flow of samples, maximally preventing the cross contamination.

Some images of the new laboratory

    FAST SERVICE, REDUCED FEE

  Thanks to the upgraded and standardized laboratory, CGAT now is able to carry out the experiments faster and to reduce the fees significantly. Especially in all cases, which require to full fill quickly, the fees are much lower, as low as 35% off.

See new price list


 
About CGAT
Giamdoc      

Mrs. NGUYỄN THỊ NGA - Director of CGAT

POLYMERASE CHAINREACTION AND DNA FINGERPRINTING

The idea to study and apply molecular genetics in Vietnam appeared in our mind since 1988, originating from Kary Mulis's discovery on Polymerase Chain Reaction (PCR), and when we could buy a thermocycler in Moscow (see photo) on the way back to Vietnam from the XVIth  International Congress of Genetics held in Toronto, Canada (September,1988). The trip was sponsored by a Dutch Project named VH3.

Nowadays, PCR has became a routine technique in the laboratories of Molecular Biology all over the World. However, the most practical application of PCR is DNA testing. Recently in a meeting of world wide experts on technologies, 25 most advanced innovations, made during the passed 25 years has been chosen, having strong influence on the human life at present and in future. DNA testing was among them and it is unique in the field of Medicine and Biology (CNN source, January 2005).

 

 APPLICATION OF DNA FINGERPRINTING IN VIETNAM

During the passed 20 years in the framework of different research topics we have obtained the results as follows:

  • Over 2000 experiments were carried out.
  • The allele frequencies of 40 polymorphic loci in Vietnamese were determined with 200-3000 samples for each allele. At the moment 10 other loci are under investigation for determination of their allelic frequencies.
  • At present each relationship test reaches 99,999% accuracy as minimum.
  • Up to now we have made paternity tests for over 7,000 families on volunteer's basis or for courts and embassies.
  • We train many technicians for the national institutions of forensic profile.
  • Nowadays our Center has close cooperation with several over-sea universities and research centers to meet the practical demands of Vietnam, as well as to improve the knowledge and skills for our staff.

DNA TYPING FOR SKELETAL REMAINS

    At present there are 4 kinds of markers, which are used in DNA typing skeletal remains. These are markers on mtDNA, miniSTR, Y-STR and SNPs. The first one locates on mtDNA. The rest three kinds of markers relay on nuclear DNA. Each kind of markers has its own advantages and disadvantages. Depending on the level of a sample degradation one can choose suitable kind of markers. In cases the DNA degradation level is low one can choose the markers located on cell nuclei. The accuracy of the test will be higher.  In cases the sample degradation level is high, the kind of markers should be chosen, is mtDNA. The accuracy is lower and the test time takes several weeks.

   In Vietnam now all the labs are using mtDNA markers, except   CGAT (Center for Genetic Analysis and Technologies), which applies both mtDNA and nuclear DNA for typing ancient samples. 

  Skeletal remains samples for typing may be a piece of bone (2-3g) or 1-2 teeth. The samples should be stored in dry and cool places before delivering to CGAT.  Control samples are taken from maternal relatives of the remains in case of mtDNA typing. For nuclear DNA typing, control samples can be taken from brothers or children of the remains sample.  

     It takes 7 days for mtDNA typing and 5 days for nuclear DNA typing.
 

CGAT ON TELEVISION

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AS NO SEPARATION WAS

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FOREIGN MEDIA

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THE MEDIA PANORAMA

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BOOKS & JOURNALS

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STATUTORY DOCUMENTS

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